Brussels Center for Redox Biology


Welcome to the

Center for Redox Biology

The Brussels Center for Redox Biology was founded in 2006 by Jean-François Collet and Joris Messens. Today, it results from a strong collaboration between the research groups of Joris Messens (VIB-VUB Center for Structural Biology), Jean-François Collet (de Duve Institute, Université Catholique de Louvain), and Frank Van Breusegem (VIB-UGent Center for Plant Systems Biology). The Center benefits from a combined expertise in biochemistry, structural biology, plant biology and microbiology.

We investigate proteins and pathways that are involved in redox signaling and oxidative protein folding. We want to understand the complex networks of interactions induced to survive cellular oxidative stress.


About us



In the Picture



Recent research published in J Biol Chem

The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.

Rosado LA, Wahni K, Degiacomi G, Pedre B, Young D, de la Rubia AG, Boldrin F, Martens E, Marcos-Pascual L, Sancho-Vaello E, Albesa-Jové D, Provvedi R, Martin C, Makarov V, Versées W, Verniest G, Guerin ME, Mateos LM, Manganelli R, Messens J.

J Biol Chem. 2017 Aug 11;292(32):13097-13110. doi: 10.1074/jbc.M117.797837. Epub 2017 Jun 15.

PMID: 28620052

VUB | VIB | de Duve Institute

Copyright 2017