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Brussels Center for Redox Biology

Job opportunities

Postdoctoral researcher in structural biology for the study of redox sensitive proteins


Position: A postdoctoral research position is immediately available for structure-function studies of proteins involved in redox metabolite signaling. Successful candidates will join the exciting research environment of the Messens VIB-laboratory at the Center for Structural Biology in Brussels, Belgium. The Messens laboratory is recognized as a world leader in the redox field, and the lab provides an outstanding position in protein biochemistry and structural biology, in a highly dynamic and team-oriented research group. In this cutting-edge research environment, you will tackle essential biological problems in metabolite signaling.


Mission of the lab: We decipher how cells sense redox metabolites and transduce stimuli into downstream biological effects. Knowledge of the mechanisms by which sensors and transducers function are invaluable in understanding how redox homeostasis pathways can be engineered with the ultimate goal of improving oxidative stress resistance in plants and to identify therapeutic targets in diseases such as diabetes and cancer, which have been associated with aberrant redox signaling.


Your role in the lab: You will be involved in a project that exploits prokaryotic proteins for the de novo design of biosensors with a fluorescent read-out for both in vitro studies and live imaging of cellular metabolic changes. Further, your expertise will be needed for the structural and functional analysis of plant H2O2-sensing proteins to explore how organelle communication functions at the molecular level.


Requirements: Applicants should have obtained a PhD in the last 5 years within the field of structural biology and should have hands-on expertise with protein purification, protein crystallization, diffraction data collection at synchrotron beamlines, and solving protein crystal structures. Fluency in English is a must. Experience with biophysical techniques is a plus, but not required.


Please include a cover letter discussing your interests in our laboratory and projects as well as your CV and a list of 3 individuals as references when applying to Jobsoid (https://vibvzw.jobsoid.com/j/16843/postdoctoral-researcher-in-structural-biology-for-the-study-of-redox-sensitive-proteins).





CSC PhD for the study of redox senstive proteins in plants



Position: A PhD position is immediately available in the Messens lab at VIB-VUB Center for Structural Biology in Brussels, Belgium for an eligible student who successfully applies and is awarded a Chinese Scholarship Council (CSC) grant in protein biochemistry and structural biology. The VIB is an exciting, world renowned place in Europe, and the Messens lab is recognized as a world leader in the redox field with a strong track record of high-impact publications. The lab provides a cutting-edge protein biochemistry and structural biology research environment in a highly dynamic and team-oriented international research group where you will tackle essential biological problems in redox signaling.


Mission of the lab: We decipher how cells sense redox metabolites and transduce these stimuli into downstream biological effects. Knowledge of the mechanisms by which sensors and transducers function are invaluable in understanding how redox homeostasis pathways can be engineered. This in turn provides ways to improve oxidative stress resistance in plants and to identify therapeutic targets for diseases such as diabetes and cancer.


Your role in the lab: Your project, as part of the Excellent of Science (EOS)-project 'Organellar Redox Signaling in Plants', will focus on structure-function studies of plant proteins that participate in redox signaling cascades. You will thereby address vital outstanding biological problems in plant redox signaling. This exciting project will likely yield high-caliber results suitable for publication in top journals.


Requirements: Applicants should have obtained a Master of Science degree with great or greatest distinction. Expertise in molecular biology, protein biochemistry, biophysical techniques and enzymology is essential. Fluency in English is a must. Knowledge of plant physiology is an asset. We will finance you with an EOS-fellowship, and support your CSC fellowship application.


Please include a cover letter discussing your interests in our lab and projects as well as your CV and a list of 3 individuals as references when applying via Jobsoid. https://app.jobsoid.com/App/#/Jobs/17608/Info